“Our findings have implications for the… design of anti-COVID-19 vaccines that are administered repeatedly as booster shots… As loss of p53 function is a known driver of cancer development and confers chemo-resistance, our study provides insight into cellular mechanisms by which SARS-CoV-2 spike may be involved in reducing barriers to tumorigenesis during and post SARS-CoV-2 infections.”
Zhang S., El-Deiry W. S.
“Transfected SARS-CoV-2 spike DNA for mammalian cell expression inhibits p53 activation of p21(WAF1), TRAIL Death Receptor DR5 and MDM2 proteins in cancer cells and increases cancer cell viability after chemotherapy exposure.”
Oncotarget. 2024; 15: 275-284.
Retrieved from https://www.oncotarget.com/article/28582/text/